June 25, 2015

Funding Opportunities NSF and NIH

National Science Foundation (NSF)

Program Title:

Advances in Biological Informatics (ABI)

PROGRAM SOLICITATION 
NSF 15-582

REPLACES DOCUMENT(S):
NSF 12-567

Full Proposal Deadline(s) (due by 5 p.m. proposer's local time):

September 22, 2015

September 09, 2016

Synopsis of Program:

The Advances in Biological Informatics (ABI) program seeks to encourage new approaches to the analysis and dissemination of biological knowledge for the benefit of both the scientific community and the broader public. The ABI program is especially interested in the development of informatics tools and resources that have the potential to advance- or transform- research in biology supported by the Directorate for Biological Sciences at the National Science Foundation. The ABI program accepts three major types of proposals: Innovation awards that seek to pioneer new approaches to the application of informatics to biological problems, Development awards that seek to provide robust cyberinfrastructure that will enable transformative biological research, and Sustaining awards that seek to support ongoing operations and maintenance of existing cyberinfrastructure that is critical for continued advancement of priority biological research.

http://www.nsf.gov/pubs/2015/nsf15582/nsf15582.htm?WT.mc_id=USNSF_25&WT.mc_ev=click

 

National Institutes of Health (NIH)

Funding Opportunity Title

Maximizing Investigators' Research Award for New and Early Stage Investigators (R35)

Funding Opportunity Announcement (FOA) Number

RFA-GM-16-003

Key Dates

Letter of Intent Due Date(s)

August 9, 2015

Application Due Date(s)

September 9, 2015, by 5:00 PM local time of applicant organization.

Funding Opportunity Purpose

The Maximizing Investigators' Research Award (MIRA) is a grant to provide support for all of the research in an investigator's laboratory that falls within the mission of NIGMS.  The goal of MIRA is to increase the efficiency and efficacy of NIGMS funding.  It is anticipated that the new mechanism will:

  • Increase the stability of funding for NIGMS-supported investigators, which could enhance their ability to take on ambitious scientific projects and approach problems more creatively.
  • Increase flexibility for investigators to follow important new research directions as opportunities arise, rather than being bound to specific aims proposed in advance of the studies.
  • More widely distribute funding among the nation’s highly talented and promising investigators to increase overall scientific productivity and the chances for important breakthroughs.
  • Reduce the time spent by researchers writing and reviewing grant applications, allowing them to spend more time conducting research.
  • Enable investigators to devote more time and energy to mentoring junior scientists in a more stable research environment.

The purpose of this FOA is to test the feasibility of this grant mechanism for New and Early Stage Investigators through a pilot program with restricted eligibility. 

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

See more at: http://grants.nih.gov/grants/guide/rfa-files/RFA-GM-16-003.html#sthash.KqIkd55z.dpuf

 

National Institutes of Health (NIH)

Funding Opportunity Title

Exploratory Studies for Delineating Microbiome:  Host Interactions in Obesity, Digestive and Liver Diseases and Nutrition (R21)

Funding Opportunity Announcement (FOA) Number

RFA-DK-15-013

Funding Opportunity Purpose

This Funding Opportunity Announcement invites applications that explore and interrogate functional interactions between human gut microbiome and host interactions in obesity, digestive and liver diseases and nutrition.

Key Dates

Posted Date

June 19, 2015

Open Date (Earliest Submission Date)

September 15, 2015

Letter of Intent Due Date(s)

30 days prior to the application due date

Application Due Date(s)

October 15, 2015 and October 19, 2016, by 5:00 PM local time of applicant organization.

Funding Opportunity Description

This Funding Opportunity Announcement (FOA) invites exploratory research projects to discover functional elements of host-microbiota interactions that modulate specific host phenotypes related to obesity, digestive and liver diseases and explore the role of microbiome in nutrition.  Applicants are encouraged to propose new directions/approaches for screening and identifying relevant microbial functions beyond association studies.  Projects are expected to bring together investigators with relevant expertise in physiology, assay platforms, screening, microbiology, etc., as appropriate. While preliminary data is not required for responding to this FOA, the project should be justified from prior association studies and should also include rationale for the feasibility of the proposed discovery-based approach.  In addition, applications that explore mere associations and/or are limited to the exploration of metagenomic sequencing are not considered responsive this FOA. Both basic and well-justified clinical and translational studies are suitable for this FOA. Exploratory projects should be relevant to digestive or liver diseases, obesity, and/or exploring the role of nutrition in these diseases and shaping microbial interactions, and may include but are not limited to:

  • Developing phenotypic assays or assay platforms to screen the human gastrointestinal microbiome or components of the human microbiome
  • Developing genetic screens to identify functional elements of human-associated microbial strains or model communities that modulate host gut and/or microbial phenotypes
  • Constructing integrated biomimetic culture systems to model communication between microbial communities, the intestinal epithelium, and mucosal immune system
  • Computational screening of multi-omic profiles to identify putative microbe-derived products that can be tested in functional assays
  • Exploration of microbiome on nutrient-nutrient interactions, and/or characterization of diet-microbiome interactions, those play a vital role in the pathophysiology of digestive or liver diseases and obesity

See more at: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-15-013.html#sthash.ntgxl6BI.dpuf

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